BioCentury
ARTICLE | Discovery & Translation

Decoding the molecular roots of pregnancy complications: Literature Dive

Blueprints for biomarker discovery and precision medicine in maternal-fetal health

May 28, 2025 11:19 PM UTC

Half a dozen recent publications offer molecular resources for understanding the biology of pregnancy, identifying biomarkers and guiding development of targeted therapies and preventive strategies for pregnancy-related conditions.

In this fourth installment of BioCentury’s series on women’s health “atlases,” BioCentury identified seven studies that employed multi-omics and spatial profiling in human tissue samples to unravel the molecular and cellular mechanisms that govern healthy pregnancy and underlie complications such as hypertension and diabetes. ...